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Product description

Note:
1. Hair can be straightened or curled using a curling iron, but the temperature should be below 180 degrees Celsius
2. Due to dryness, oil and dirt build up, salt water and uncombed (wide tooth comb) hair can tangles hairMake sure to wash your hair at least once a week, and if possible, twice a week.
3. Pay attention to the maintenance method, treat it like your own hair, and maintain it for a long time
4.The color of the actual items may slightly vary from the above images due to different computer screen. thanks for your understanding.

Usually we will deliver your parcel within 10-15 business days, even faster. However, due to the impact of customs clearance and local post offices, weather, and national policies, there may be occasional delays in delivery. If there is a delivery delay, please contact us and we will contact the logistics carrier to resolve the delivery problem as soon as possible.

Please ensure that all your address contact information is correct. If the delivery fails due to incorrect receipt information, we will not be liable. After the package is shipped by the logistics carrier, it cannot be cancelled during transportation; please sign the package in time. We are not responsible for the failure to sign the parcel in time for the customer's own reasons, resulting in the return or loss of the parcel.

Understanding and respect are mutual. Communication is the solution to all problems. If you have any questions, ple

LCNING Rin Hoshizora Cosplay Wig LoveLive! Love Live Costume Pla

Since Jan 2010, Selleckchem products have been cited in 415 studies from top scientific journals.

Thirteen Nobel Prize winners have published 44 articles with Selleck products.

THE NOBEL PRIZE

Michael Houghton

Won the Nobel Prize in Physiology or Medicine in 2020

Charles M. Rice

Won the Nobel Prize in Physiology or Medicine in 2020

  • Nat Commun, 2020, 11(1):1677
  • bioRxiv, 2020, 2020.10.09.334128
  • bioRxiv, 2020, 2020.01.20.910927
  • Viruses, 2019, 11(11)E1039
  • Cell Rep, 2018, 25(4):833-840.e3
  • Cell, 2018, 172(3):423-438.e25
  • Gastroenterology, 2017, 153(2):566-578.e5
  • Gastroenterology, 2016, 150(1):82-85.e4
  • Antimicrob, 2016, 60(6):3786-93
  • Nature, 2015, 524(7566):471-5
  • Antimicrob, 2015, 59(6):3482-92
  • J Virol, 2014, 88(20):12098-111

    PubMed: 25122776

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  • Antimicrob, 2014, 58(9):5386-94
  • J Virol, 2013, 87(13):7593-607
  • Nature, 2013, 501(7466):237-41
  • Nature, 2013, 99(1):6-11
  • Antimicrob, 2012, 56(10):5365-73

James P. Allison

Won the Nobel Prize in Physiology or Medicine in 2018

Michael Rosbash

Won the Nobel Prize in Physiology or Medicine in 2017

Eric Richard Kandel

Won the Nobel Prize in Physiology or Medicine in 2000

Brian K. Kobilka

Won the Nobel Prize in Chemistry in 2012

Robert Lefkowitz

Won the Nobel Prize in Chemistry in 2012

Aaron Ciechanover

Won the Nobel Prize in Chemistry in 2004

New Products

Catalog No. Product Name Target Pathway Information
S8944 G150 Others Others G150 is a potent and highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with IC50 of 10.2 nM.
S8913 TH5487 Others Others TH5487 is a selective active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM.
S8938 KGA-2727 SGLT GPCR & G Protein KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models.
S8939 Mizagliflozin SGLT GPCR & G Protein Mizagliflozin is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation.
S7013 Guadecitabine (SGI-110) Others Others Guadecitabine (SGI-110) is a next-generation hypomethylating agent whose active metabolite decitabine has a longer in-vivo exposure time than intravenous decitabine.
S8812 CM272 DNA Methyltransferase Epigenetics CM-272 is a novel first-in-class dual reversible inhibitor of G9a (GLP) and DNMTs with IC50 of 8 nM, 382 nM, 85 nM, 1200 nM, 2 nM for G9a, DNMT1, DNMT3A, DNMT3B, GLP, respectively. CM-272 prolongs survival in in vivo models of haematological malignancies by at least in part inducing immunogenic cell death.
S9729 Visomitin (SKQ1) Others Others INT-777 (S-EMCA) is a novel potent and selective TGR5 agonist with EC50 values of 0.18 μM, 3.9 μM and 1.45 μM for WT TGR5, TGR5(N76A) and TGR5(Y89F) respectively.
S8500 BAY1125976 Akt PI3K/Akt/mTOR BAY 1125976 is a selective allosteric AKT1/2 inhibitor,exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. BAY1125976 inhibits the activity of AKT1 (IC50 = 5.2 nM at 10 µM ATP and 44 nM at 2 mM ATP) and AKT2 (IC50 = 18 nM at 10 µM ATP and 36 nM at 2 mM ATP) very potently.Whereas BAY1125976 is almost inactive on AKT3 (IC50 = 427 nM at 10 µM ATP).
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Tags: kinase inhibitors, tyrosine kinase inhibitors, enzyme inhibitors, protein inhibitors, proteins kinase inhibitors, small molecules, phosphatase inhibitors